Description

(R)-1-(2,6-Difluorophenyl)Ethanamine-Hcl CAS NO 1217453-91-2 is a high-purity chiral amine hydrochloride salt, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, which is essential for achieving desired biological activity and pharmacokinetic properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Employed in methodological studies and the synthesis of complex natural products or novel molecular architectures.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring a specific (R)-configured amine moiety.

Basic Information

Product Name	(R)-1-(2,6-Difluorophenyl)Ethanamine Hydrochloride
CAS No.	1217453-91-2
Molecular Formula	C8H10ClF2N
Molecular Weight	193.62 g/mol
Synonyms	(R)-1-(2,6-Difluorophenyl)ethanamine hydrochloride; (R)-α-Methyl-2,6-difluorobenzylamine hydrochloride; (R)-2,6-Difluoro-α-methylbenzylamine HCl; (R)-1-(2,6-Difluorophenyl)ethylamine hydrochloride; (R)-2,6-DFPEA·HCl; (R)-1-Aminoethyl-2,6-difluorobenzene hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2,6-Difluorophenyl)Ethanamine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.