Description

(S)-2-Azido-4-(Methylthio)Butanoic Acid Cyclohexylammonium Salt is a high-purity, non-natural amino acid derivative featuring a reactive azide group and a methylthioether side chain, stabilized as a cyclohexylammonium salt. This compound is a critical chiral building block for the synthesis of complex bioactive molecules, enabling precise structural modifications. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers in the development of novel drug candidates, particularly in peptide mimetics and targeted bioconjugates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential protease inhibitors and other small-molecule therapeutics.
• Peptidomimetic Research: Used to incorporate azide-functionalized, sulfur-containing amino acid analogs into peptide backbones for structure-activity relationship (SAR) studies.
• Click Chemistry Substrate: The azide group readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Chemical Biology Probes: Enables the site-specific labeling of proteins or other biomolecules for imaging, diagnostics, and target identification.
• Agrochemical Synthesis: Serves as a precursor in the development of novel chiral active ingredients with specific biological activity.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies and novel chemical entities in medicinal chemistry.

Basic Information

Product Name	(S)-2-Azido-4-(Methylthio)Butanoic Acid Cyclohexylammonium Salt
CAS No.	1217445-93-6
Molecular Formula	C11H22N4O2S
Molecular Weight	274.38 g/mol
Synonyms	Cyclohexylammonium (2S)-2-azido-4-(methylsulfanyl)butanoate; (S)-2-Azido-4-(methylthio)butyric Acid Cyclohexylamine Salt; L-2-Azido-4-(methylthio)butanoic Acid Cyclohexylammonium Salt; (S)-2-Azido-4-(methylmercapto)butanoic Acid Cyclohexylammonium Salt; Azido-Met-OH•CHA Salt; (2S)-2-Azido-4-(methylsulfanyl)butanoic Acid - Cyclohexanamine (1:1); A building block for peptide synthesis.
EINECS	Contact for details

Quality Control

Every batch of (S)-2-Azido-4-(Methylthio)Butanoic Acid Cyclohexylammonium Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Chiral Purity (HPLC)	≥98.0% ee
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.