Description

[4-(2-Propyn-1-Yloxy)Phenyl]Amine Hydrochloride is a high-purity organic intermediate featuring a reactive aniline core functionalized with a propargyl ether group. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in click chemistry and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions due to its terminal alkyne functionality for bioconjugation and polymer synthesis.
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the creation of specialty polymers, dendrimers, and functionalized surfaces.
• Chemical Biology Probes: Serves as a precursor for labeling reagents and molecular probes used in biochemical assays.
• Ligand and Catalyst Development: Building block for synthesizing novel ligands for metal complexes and organocatalysts.

Basic Information

Product Name	[4-(2-Propyn-1-Yloxy)Phenyl]Amine Hydrochloride
CAS No.	1217129-50-4
Molecular Formula	C9H10ClNO
Molecular Weight	183.63 g/mol
Synonyms	4-(Prop-2-yn-1-yloxy)aniline hydrochloride; 4-(Propargyloxy)aniline hydrochloride; 1-Amino-4-(prop-2-yn-1-yloxy)benzene hydrochloride; p-(Propargyloxy)aniline HCl; 4-Aminophenyl propargyl ether hydrochloride; N-(4-Hydroxyphenyl)propargylamine hydrochloride (tautomeric form); Propargyl 4-aminophenyl ether hydrochloride
EINECS	Contact for details

Quality Control

Our [4-(2-Propyn-1-Yloxy)Phenyl]Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.