Description

(3-Methyl-1H-Pyrazol-4-Yl)Methanamine Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block and intermediate. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and pesticides.
• Bioconjugation & Probe Development: The amine functional group allows for conjugation to biomolecules, peptides, or fluorescent tags for diagnostic and research applications.
• Chemical Biology: Employed in the design and synthesis of chemical probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex molecules under cGMP or research-grade conditions.

Basic Information

Product Name	(3-Methyl-1H-Pyrazol-4-Yl)Methanamine Dihydrochloride
CAS No.	1216924-62-7
Molecular Formula	C5H11Cl2N3
Molecular Weight	184.07 g/mol
Synonyms	4-(Aminomethyl)-3-methyl-1H-pyrazole dihydrochloride; 1H-Pyrazole-4-methanamine, 3-methyl-, dihydrochloride; (3-Methyl-1H-pyrazol-4-yl)methanamine hydrochloride (1:2); 3-Methyl-1H-pyrazole-4-methylamine dihydrochloride; 4-(Aminomethyl)-3-methylpyrazole dihydrochloride
EINECS	Contact for details

Quality Control

Our (3-Methyl-1H-Pyrazol-4-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.