Description

7H-Pyrrolo[3,2-F]Quinazoline-1,3-Diamine, N3-Cyclopropyl-7-[[4-(1-Methylethyl)Phenyl]Methyl]-, (Hydrochloride) (1:2) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in targeted drug discovery programs, particularly in oncology and kinase inhibition. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and CDMOs (Contract Development and Manufacturing Organizations) engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for cancer therapy.
• Biochemical Research: Used as a reference standard and probe molecule in enzymatic assays and target validation studies.
• Preclinical Development: Serves as a critical starting material for the scale-up and process optimization of candidate drug molecules.
• Academic Research: Employed in medicinal chemistry programs focused on heterocyclic compound synthesis and structure-activity relationship (SAR) studies.
• Custom Synthesis: Basis for the development of proprietary analogs and derivatives for specialized research applications.

Basic Information

Product Name	7H-Pyrrolo[3,2-F]Quinazoline-1,3-Diamine, N3-Cyclopropyl-7-[[4-(1-Methylethyl)Phenyl]Methyl]-, (Hydrochloride) (1:2)
CAS No.	1216720-69-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N3-Cyclopropyl-7-[(4-isopropylbenzyl)]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride; 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, N3-cyclopropyl-7-[(4-isopropylphenyl)methyl]-, hydrochloride (1:2); 1216720-69-2; N3-Cyclopropyl-7-(4-isopropylbenzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride; Kinase Inhibitor Intermediate; Pyrroloquinazoline Dihydrochloride Salt
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.