Description

N4-tert-Butoxycarbonyl-1-[2-(2-Hydroxyethoxy)Ethyl]Piperazine N1-Oxide is a specialized, high-purity chemical building block featuring a protected piperazine N-oxide core. This compound is critical for synthetic chemists requiring a versatile, functionalized intermediate with orthogonal protecting groups for complex multi-step synthesis. It is primarily utilized in advanced pharmaceutical research and development, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and sophisticated ligands.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Ligand Synthesis: Used to create sophisticated chelating agents and ligands for catalysis and metal complexation studies.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Bioconjugation: The reactive hydroxyl and protected amine groups enable its use in linking pharmacophores or creating antibody-drug conjugates (ADCs).
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular processes.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and herbicides.

Basic Information

Item	Details
Product Name	N4-tert-Butoxycarbonyl-1-[2-(2-Hydroxyethoxy)Ethyl]Piperazine N1-Oxide
CAS No.	1216684-15-9
Molecular Formula	C13H26N2O5
Molecular Weight	290.36 g/mol
Synonyms	1-[2-(2-Hydroxyethoxy)ethyl]-4-[(2-methylpropan-2-yl)oxycarbonyl]piperazine 1-oxide; tert-Butyl 1-oxido-4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-ium-1-carboxylate; Boc-Pip(O)-OH-ethoxylate; 4-Boc-1-(2-(2-hydroxyethoxy)ethyl)piperazine 1-oxide; N-Boc-N'-(2-(2-hydroxyethoxy)ethyl)piperazine N-oxide; 1216684-15-9; Piperazine N-oxide derivative
EINECS	Contact for details

Quality Control

Our production of N4-tert-Butoxycarbonyl-1-[2-(2-Hydroxyethoxy)Ethyl]Piperazine N1-Oxide adheres to stringent quality protocols suitable for research and cGMP-grade applications. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure structural integrity and purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.