Description

6-(Piperidin-4-Ylmethoxy)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining nicotinic acid and piperidine moieties. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of targeted therapeutics, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation & Probe Development: Utilized in the creation of chemical probes and affinity labels for biological target identification and validation.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	6-(Piperidin-4-Ylmethoxy)Nicotinic Acid
CAS No.	1216644-32-4
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	6-[(Piperidin-4-yl)methoxy]pyridine-3-carboxylic acid; 6-((Piperidin-4-yl)methoxy)nicotinic acid; Nicotinic acid, 6-(4-piperidinylmethoxy)-; 1216644-32-4; 6-(Piperidin-4-ylmethoxy)nicotinic acid; 6-(4-Piperidylmethoxy)nicotinic acid; 6-Piperidin-4-ylmethoxynicotinic acid
EINECS	Contact for details

Quality Control

Our 6-(Piperidin-4-Ylmethoxy)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates in development and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.