Description

6-Aminohexyl Methanthiosulfonate Hydrobromide is a specialized bifunctional chemical reagent featuring a reactive methanethiosulfonate (MTS) group and a primary amine. This compound is engineered for the site-directed modification of proteins and other biomolecules, enabling controlled disulfide bond formation or thiol-specific labeling. It is an essential tool for researchers and manufacturers in bioconjugation, proteomics, and pharmaceutical development, where precise molecular engineering is required.

Application

• Bioconjugation Reagent: For the site-specific cross-linking or labeling of cysteine residues in proteins and peptides.
• Protein Engineering: Used to introduce stable disulfide bonds or attach functional probes (e.g., fluorophores, biotin) to biomolecules.
• Antibody-Drug Conjugate (ADC) Development: Serves as a linker precursor for constructing stable, cleavable linkages between cytotoxic drugs and monoclonal antibodies.
• Surface Functionalization: Modifying gold nanoparticles, biosensors, or chromatographic media via the thiol-reactive MTS group.
• Proteomics Research: A tool for studying protein structure, function, and interactions through controlled chemical modification.
• Polymer Chemistry: Acts as a monomer or modifier for synthesizing functional polymers with amine and disulfide exchange capabilities.

Basic Information

Product Name	6-Aminohexyl Methanthiosulfonate Hydrobromide
CAS No.	1216618-83-5
Molecular Formula	C7H16BrNO2S2
Molecular Weight	282.24 g/mol
Synonyms	6-(Methanesulfonothioyloxy)hexan-1-aminium bromide; 6-Aminohexyl methanethiosulfonate HBr; AHMTS-HBr; 1-Amino-6-(methanethiosulfonato)hexane hydrobromide; Hexane-1,6-diamine, N-(methanesulfonothioyl)-, hydrobromide; MTS-NH2(C6) HBr; Aminohexyl MTS hydrobromide
EINECS	Contact for details

Quality Control

Every batch of 6-Aminohexyl Methanthiosulfonate Hydrobromide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and consistency. Our quality assurance protocol includes identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your research and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.