Description

4-Chloro-1-(2,5-Difluorophenyl)Butan-1-One is a high-value, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring both chloro and difluoro substituents, provides a versatile handle for constructing complex molecules with tailored electronic and steric properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and creating novel chemical libraries for high-throughput screening.

Basic Information

Product Name	4-Chloro-1-(2,5-Difluorophenyl)Butan-1-One
CAS No.	1216260-42-2
Molecular Formula	C10H9ClF2O
Molecular Weight	218.63 g/mol
Synonyms	1-(2,5-Difluorophenyl)-4-chlorobutan-1-one; 4-Chloro-1-(2,5-difluorophenyl)-1-butanone; 4-Chloro-1-(2,5-difluorophenyl)butan-1-one; Butan-1-one, 4-chloro-1-(2,5-difluorophenyl)-; 4-Chloro-2',5'-difluorobutyrophenone; γ-Chloro-2,5-difluoropropiophenone; 1216260-42-2; 4-Chloro-1-(2,5-difluorophenyl)butanone
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(2,5-Difluorophenyl)Butan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.