Description

5-Bromo-7-Chloroquinolin-8-Amine is a high-purity, multi-halogenated quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical intermediates and functional materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting infectious diseases or with specific receptor activity.
• Agrochemical Research: Used in the development of new fungicides, herbicides, or insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, ligands for metal-organic frameworks (MOFs), or photoactive materials.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions, nucleophilic substitutions, or metal-catalyzed transformations.
• Dye & Pigment Industry: Potential intermediate for synthesizing specialized heterocyclic dyes and pigments due to its halogenated amine structure.

Basic Information

Product Name	5-Bromo-7-Chloroquinolin-8-Amine
CAS No.	1215767-85-3
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	8-Amino-5-bromo-7-chloroquinoline; 5-Bromo-7-chloro-8-quinolinamine; 7-Chloro-5-bromoquinolin-8-amine; Quinoline, 8-amino-5-bromo-7-chloro-; 1215767-85-3; 5-Br-7-Cl-quinolin-8-amine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-7-Chloroquinolin-8-Amine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.