Description

5-Bromo-2-Chloro-8-Fluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which enables precise structural modifications in target molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Research: Used to develop new fungicides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution, enabling library synthesis for drug discovery.
• Fluorescent Probe Development: Utilized in designing molecular probes and sensors due to the inherent photophysical properties of the quinoline structure.

Basic Information

Product Name	5-Bromo-2-Chloro-8-Fluoroquinoline
CAS No.	1215767-73-9
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	8-Fluoro-5-bromo-2-chloroquinoline; 2-Chloro-5-bromo-8-fluoroquinoline; 5-Bromo-2-chloro-8-fluoro-quinoline; Quinoline, 5-bromo-2-chloro-8-fluoro-; 1215767-73-9; 5-Br-2-Cl-8-F-quinoline
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-8-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.