Description

3-(4-Chlorobenzoyl)Piperidine Hydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in medicinal chemistry. This compound matters for its role as a versatile synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for APIs.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.

Basic Information

Product Name	3-(4-Chlorobenzoyl)Piperidine Hydrochloride
CAS No.	1215723-25-3
Molecular Formula	C12H14ClNO • HCl
Molecular Weight	260.16 g/mol (Free base: 223.70 g/mol)
Synonyms	1-(4-Chlorobenzoyl)piperidin-3-amine hydrochloride; 3-Amino-1-(4-chlorobenzoyl)piperidine hydrochloride; 4-Chloro-α-(3-piperidinyl)benzenemethanone hydrochloride; 3-(p-Chlorobenzoyl)piperidine hydrochloride; Piperidine, 3-(4-chlorobenzoyl)-, hydrochloride; 1215723-25-3
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorobenzoyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.