Description

1-(Aminomethyl)Cyclopropanol Hydrochloride is a versatile and reactive chemical building block featuring both an amino and a hydroxyl group on a strained cyclopropane ring. This unique structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on novel active ingredients. The compound, identified by CAS NO 1215417-77-8, is supplied as a high-purity salt to ensure optimal performance in sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring constrained ring systems for bioactivity.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, or insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to construct chiral ligands or organocatalysts that leverage the stereochemistry of the cyclopropane backbone for asymmetric synthesis.
• Peptidomimetics and Bioisosteres: Incorporates rigid, three-membered ring structures into peptide analogs to enhance metabolic stability and binding affinity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Functional handle for creating molecular probes to study enzyme function or cellular pathways.

Basic Information

Item	Detail
Product Name	1-(Aminomethyl)Cyclopropanol Hydrochloride
CAS No.	1215417-77-8
Molecular Formula	C4H9NO · HCl
Molecular Weight	123.58 g/mol
Synonyms	1-(Aminomethyl)cyclopropan-1-ol hydrochloride; Cyclopropanol, 1-(aminomethyl)-, hydrochloride; (1-Hydroxycyclopropyl)methanamine hydrochloride; Aminomethylcyclopropanol HCl; 1-(Aminomethyl)-1-cyclopropanol hydrochloride; (1-Aminomethyl)cyclopropanol hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 1-(Aminomethyl)Cyclopropanol Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.