Description

2-Chloro-5-Methylbiphenyl-3-Carboxylic Acid is a high-purity biphenyl carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its functionalized aromatic structure, which enables precise chemical modifications for creating complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its biphenyl core for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Functional monomer for the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Reference Standard: High-purity grade used as an analytical standard for quality control and method development in analytical laboratories.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific functionalization on the biphenyl scaffold.

Basic Information

Product Name	2-Chloro-5-Methylbiphenyl-3-Carboxylic Acid
CAS No.	1215206-22-6
Molecular Formula	C14H11ClO2
Molecular Weight	246.69 g/mol
Synonyms	3'-Chloro-6-methyl-[1,1'-biphenyl]-3-carboxylic acid; 2-Chloro-5-methyl-3-biphenylcarboxylic acid; 3-Biphenylcarboxylic acid, 2-chloro-5-methyl-; 2-Chloro-5-methylbiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-chloro-6-methyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Methylbiphenyl-3-Carboxylic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets exacting specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (IR, NMR), and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.