Description

1-Bromo-3-Chloro-2-Methoxy-5-Nitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its precise substitution pattern, which enables selective reactions for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye & Pigment Intermediate: Employed in the synthesis of complex azo dyes and high-performance pigments due to its nitro and methoxy substituents.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create biaryl and other complex structures.
• Chemical Research & Development: A versatile reagent for methodological studies in organic chemistry, including nucleophilic aromatic substitution and reduction reactions.

Basic Information

Item	Details
Product Name	1-Bromo-3-Chloro-2-Methoxy-5-Nitrobenzene
CAS No.	1215205-94-9
Molecular Formula	C7H5BrClNO3
Molecular Weight	266.48 g/mol
Synonyms	2-Bromo-6-Chloro-3-Methoxy-1-Nitrobenzene; 3-Bromo-1-Chloro-2-Methoxy-5-Nitrobenzene; 5-Nitro-2-Bromo-6-Chloroanisole; 1-Bromo-3-chloro-2-methoxy-5-nitro-benzene; Benzene, 1-bromo-3-chloro-2-methoxy-5-nitro-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-2-Methoxy-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.