Description

2-Fluoro-5-Methoxybiphenyl-3-Carboxylic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular structure, featuring both fluorine and methoxy substituents, provides valuable electronic and steric properties for constructing complex target molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Chemical Synthesis Scaffold: Employed in organic synthesis as a versatile scaffold for Suzuki-Miyaura and other cross-coupling reactions to create diverse biphenyl libraries.
• Academic & R&D: Utilized in university and corporate research laboratories for method development and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	2-Fluoro-5-Methoxybiphenyl-3-Carboxylic Acid
CAS No.	1215205-32-5
Molecular Formula	C14H11FO3
Molecular Weight	246.24 g/mol
Synonyms	3'-Fluoro-4'-methoxy-[1,1'-biphenyl]-3-carboxylic acid; 3-(3-Fluoro-4-methoxyphenyl)benzoic acid; 2-Fluoro-5-methoxy-3-biphenylcarboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-fluoro-4'-methoxy-; 3'-Fluoro-4'-methoxybiphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-5-Methoxybiphenyl-3-Carboxylic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.