Description

(S)-2-(2-Chlorophenyl)-2-Hydroxypropionic Acid CAS NO 1215178-12-3 is a high-purity chiral intermediate of significant importance in modern asymmetric synthesis. Its value lies in its role as a key building block for the production of enantiomerically pure pharmaceuticals and agrochemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for optimal activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis, including hydrogenation and carbon-carbon bond-forming reactions.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel chiral compounds with potential biological activity.
• Reference Standard: Used as an analytical standard for method development and quality control in laboratories to ensure the purity and enantiomeric excess of related compounds.

Basic Information

Product Name	(S)-2-(2-Chlorophenyl)-2-Hydroxypropionic Acid
CAS No.	1215178-12-3
Molecular Formula	C9H9ClO3
Molecular Weight	200.62 g/mol
Synonyms	(S)-2-Hydroxy-2-(2-chlorophenyl)propanoic Acid; (S)-2-Chloromandelic Acid Methyl Ester Hydrolysis Product; (S)-α-Hydroxy-2-chlorophenylpropionic Acid; L-2-(2-Chlorophenyl)-2-Hydroxypropionic Acid; (S)-2-(2-Chlorophenyl)Lactic Acid; (2S)-2-(2-Chlorophenyl)-2-hydroxypropanoic Acid; (S)-O-Desmethyl Clofibric Acid Derivative
EINECS	Contact for details

Quality Control

Our (S)-2-(2-Chlorophenyl)-2-Hydroxypropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with high-purity standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases, oxidizing agents, and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.