Description

1-Bromo-3-(Butane-1-Sulfonyl)Benzene is a high-value, organosulfur aromatic building block designed for advanced synthetic chemistry. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized in the pharmaceutical, agrochemical, and specialty chemical industries for cross-coupling reactions and as a precursor for sulfonamide derivatives.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those containing sulfonyl or aryl bromide functional groups for further derivatization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the benzene sulfonyl moiety is required for bioactivity.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Sulfonamide Library Synthesis: Essential for medicinal chemistry programs focused on creating diverse libraries of sulfonamide-based compounds for high-throughput screening.
• Chemical Biology Probes: Used to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	1-Bromo-3-(Butane-1-Sulfonyl)Benzene
CAS No.	1215077-78-3
Molecular Formula	C₁₀H₁₃BrO₂S
Molecular Weight	277.18 g/mol
Synonyms	3-Bromophenyl Butyl Sulfone; 1-Bromo-3-(butylsulfonyl)benzene; m-Bromophenyl Butyl Sulfone; Butane-1-sulfonyl-3-bromobenzene; 3-Bromobenzenebutanesulfonic Acid Sulfone; (3-Bromophenyl)(butyl)sulfone; Benzenesulfonic acid, 3-bromo-, butyl ester, S,S-dioxide; 1215077-78-3
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Butane-1-Sulfonyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.