Description

(2E)-3-(3-Bromo-2-Fluorophenyl)Prop-2-Enoic Acid is a high-purity fluorinated and brominated aromatic building block. This compound is a key intermediate in modern pharmaceutical and agrochemical synthesis, valued for its ability to introduce both halogen substituents into complex molecular frameworks. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity imparted by its halogenated structure.
• Material Science Research: Serves as a monomer or precursor for synthesizing specialized polymers and liquid crystals with unique electronic or optical properties.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-directed synthetic routes.

Basic Information

Product Name	(2E)-3-(3-Bromo-2-Fluorophenyl)Prop-2-Enoic Acid
CAS No.	1214791-57-7
Molecular Formula	C9H6BrFO2
Molecular Weight	245.05 g/mol
Synonyms	(E)-3-(3-Bromo-2-fluorophenyl)acrylic acid; trans-3-(3-Bromo-2-fluorophenyl)propenoic acid; 3-(3-Bromo-2-fluorophenyl)-2-propenoic acid; 3-(3-Bromo-2-fluorophenyl)acrylic acid; (2E)-3-(3-Bromo-2-fluorophenyl)acrylic acid; 3-(3-Bromo-2-fluorophenyl)prop-2-enoic acid; (E)-3-(3-Bromo-2-fluorophenyl)-2-propenoic acid
EINECS	Contact for details

Quality Control

Every batch of (2E)-3-(3-Bromo-2-Fluorophenyl)Prop-2-Enoic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly sealed due to the compound's light-sensitive nature.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.