Description

5-Bromo-2-Fluoroisonicotinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating next-generation compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for bioactivity and metabolic stability.
• Material Science Precursor: Serves as a building block for functionalized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-2-Fluoroisonicotinic Acid
CAS No.	1214377-40-8
Molecular Formula	C6H3BrFNO2
Molecular Weight	220.00 g/mol
Synonyms	5-Bromo-2-fluoropyridine-4-carboxylic acid; 2-Fluoro-5-bromoisonicotinic acid; 4-Pyridinecarboxylic acid, 5-bromo-2-fluoro-; 5-Bromo-2-fluoro-4-pyridinecarboxylic acid; 1214377-40-8; 5-Br-2-F-isonicotinic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoroisonicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.