Description

3-Amino-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid group on a trifluoromethylated pyridine core, makes it a critical intermediate for creating novel compounds with tailored properties. This compound is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and hydrogen-bonding capabilities.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-Amino-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	1214370-77-0
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-amino-5-(trifluoromethyl)-; 3-Amino-5-(trifluoromethyl)picolinic acid; 5-(Trifluoromethyl)-3-aminopicolinic acid; 3-Amino-5-trifluoromethylpyridine-2-carboxylic acid; 3-Amino-5-trifluoromethyl-2-pyridinecarboxylic acid; 3-Amino-5-(trifluoromethyl)-2-pyridinecarboxylic acid; 1214370-77-0
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.