Description

(5-Fluoro-2-Nitrophenyl)Methanamine Hydrochloride is a high-purity, synthetically valuable aromatic amine hydrochloride salt, primarily used as a key building block in advanced organic synthesis. Its molecular structure, featuring both a fluoro and a nitro substituent, makes it a versatile intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty dyes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antibacterial agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, fungicides, and pesticides, leveraging the reactivity of the amine and halogenated nitroaromatic system.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials where fluorinated aromatic amines are required.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex azo dyes and high-performance pigments.
• Chemical Biology & Proteomics: Employed as a reagent for bioconjugation and the synthesis of molecular probes and affinity tags.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	(5-Fluoro-2-Nitrophenyl)Methanamine Hydrochloride
CAS No.	1214366-45-6
Molecular Formula	C7H8ClFN2O2
Molecular Weight	206.60 g/mol
Synonyms	1-(5-Fluoro-2-nitrophenyl)methanamine hydrochloride; (5-Fluoro-2-nitrobenzyl)amine hydrochloride; 5-Fluoro-2-nitrobenzylamine hydrochloride; α-Amino-5-fluoro-2-nitrotoluene hydrochloride; Benzenemethanamine, 5-fluoro-2-nitro-, hydrochloride; 2-Nitro-5-fluorobenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (5-Fluoro-2-Nitrophenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.