Description

Ethyl 3,6-Difluoropicolinate is a high-value fluorinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular architecture makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials and liquid crystals due to its fluorinated aromatic core.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on proprietary client molecules.

Basic Information

Product Name	Ethyl 3,6-Difluoropicolinate
CAS No.	1214363-19-5
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	Ethyl 3,6-difluoropyridine-2-carboxylate; 3,6-Difluoropicolinic Acid Ethyl Ester; 2-Pyridinecarboxylic acid, 3,6-difluoro-, ethyl ester; Ethyl 3,6-difluoro-2-pyridinecarboxylate; 1214363-19-5; 3,6-Difluoropicolinate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3,6-Difluoropicolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.