Description

2,4'-Difluoro-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its specific fluorine substitution pattern enables precise tuning of molecular properties. It is primarily needed by research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical and agrochemical industries seeking to incorporate sophisticated biphenyl motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and thermal stability.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of high-performance polymers, such as polyesters and polyamides, for specialty plastics and coatings.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new coupling reactions and constructing complex polycyclic aromatic structures.
• Material Science: Investigated for use in metal-organic frameworks (MOFs) and other advanced materials due to its rigid biphenyl backbone and carboxylic acid functionality.

Basic Information

Item	Detail
Product Name	2,4'-Difluoro-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1214332-32-7
Molecular Formula	C₁₃H₈F₂O₂
Molecular Weight	234.20 g/mol
Synonyms	3-Carboxy-2,4'-difluorobiphenyl; 2,4'-Difluorobiphenyl-3-carboxylic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 2,4'-difluoro-; 2,4'-DFBA; 2,4'-Difluoro-3-biphenylcarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2,4'-Difluoro-[1,1'-Biphenyl]-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.