Description

2-Carboxymethyl-5-Chloro-3-Fluoropyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, fluoro, and carboxymethyl substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs where the fluorine atom enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the chloro and fluoro substituents for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials that require specific electronic or steric properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Carboxymethyl-5-Chloro-3-Fluoropyridine
CAS No.	1214323-94-0
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	5-Chloro-3-fluoro-2-pyridineacetic acid; 2-Pyridineacetic acid, 5-chloro-3-fluoro-; (5-Chloro-3-fluoropyridin-2-yl)acetic acid; 5-Chloro-3-fluoropyridine-2-acetic acid; 2-(5-Chloro-3-fluoropyridin-2-yl)acetic acid; CAS 1214323-94-0
EINECS	Contact for details

Quality Control

Every batch of 2-Carboxymethyl-5-Chloro-3-Fluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.