Description

2-Bromo-6-Fluro-4-Pyridinecarboxylic Acid is a high-value halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the halogenated pyridine core contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-6-Fluro-4-Pyridinecarboxylic Acid
CAS No.	1214323-63-3
Molecular Formula	C6H3BrFNO2
Molecular Weight	219.99 g/mol
Synonyms	2-Bromo-6-fluoroisonicotinic acid; 4-Pyridinecarboxylic acid, 2-bromo-6-fluoro-; 6-Fluoro-2-bromopyridine-4-carboxylic acid; 2-Bromo-6-fluoropyridine-4-carboxylic acid; 2-Bromo-6-fluoro-4-carboxypyridine; 1214323-63-3; Bromofluoroisonicotinic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluro-4-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with every shipment to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.