Description

(Dimethylamino)(3-Fluorophenyl)Acetic Acid Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant interest in modern organic synthesis. Its core value lies in its versatile molecular scaffold, which incorporates both a dimethylamino group and a fluorinated aromatic ring, making it a critical precursor for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fluorinated organic compounds for various high-value applications.

Basic Information

Product Name	(Dimethylamino)(3-Fluorophenyl)Acetic Acid Hydrochloride
CAS No.	1214126-90-5
Molecular Formula	C10H13FNO2 • HCl
Molecular Weight	233.68 g/mol (Free base)
Synonyms	2-(Dimethylamino)-2-(3-fluorophenyl)acetic acid hydrochloride; 3-Fluoro-α-(dimethylamino)benzeneacetic acid hydrochloride; (3-Fluorophenyl)(dimethylamino)acetic acid hydrochloride; DMAPA-F HCl; N,N-Dimethyl-3-fluoro-phenylglycine hydrochloride; α-(Dimethylamino)-3-fluorophenylacetic acid HCl; NSC 876128 (Hydrochloride salt)
EINECS	Contact for details

Quality Control

Every batch of (Dimethylamino)(3-Fluorophenyl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.