Description

2-Methyl-1,3,7-Triaza-Spiro[4.5]Dec-1-En-4-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system (CNS) and other specialized therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the exploration of new bioactive molecules in drug discovery programs.
• API Development: Used in process chemistry for the scale-up and optimization of synthetic routes leading to potential new active pharmaceutical ingredients.
• Contract Synthesis: Supplied to CDMOs and fine chemical manufacturers for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry, spiro compound reactivity, and novel synthetic methodologies.

Basic Information

Product Name	2-Methyl-1,3,7-Triaza-Spiro[4.5]Dec-1-En-4-One Hydrochloride
CAS No.	1214028-87-1
Molecular Formula	C9H15ClN4O
Molecular Weight	230.70 g/mol
Synonyms	2-Methyl-1,3,7-triazaspiro[4.5]dec-1-en-4-one hydrochloride; 1,3,7-Triazaspiro[4.5]dec-1-ene-4-one, 2-methyl-, hydrochloride; 2-Methyl-1,3,7-triazaspiro[4.5]dec-1-en-4-one HCl; Spiro[4.5]decane derivative, 2-methyl-1,3,7-triaza-1-en-4-one hydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Methyl-1,3,7-Triaza-Spiro[4.5]Dec-1-En-4-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.