Description

(S)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine-Hcl CAS NO 1213939-94-6 is a high-purity chiral amine building block, specifically the hydrochloride salt of the (S)-enantiomer. This compound is a critical intermediate for the synthesis of advanced pharmaceutical agents and agrochemicals, where its defined stereochemistry is essential for biological activity. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the specific stereochemistry influences efficacy and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create other enantiomerically pure compounds.
• Fine Chemical Manufacturing: Employed in the synthesis of complex, high-value specialty chemicals for electronics, materials science, and performance additives.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(S)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine Hydrochloride
CAS No.	1213939-94-6
Molecular Formula	C9H11ClF3N
Molecular Weight	225.64 g/mol
Synonyms	(S)-1-[3-(Trifluoromethyl)phenyl]ethanamine hydrochloride; (S)-α-Methyl-3-(trifluoromethyl)benzylamine hydrochloride; (S)-1-(3-Trifluoromethylphenyl)ethylamine HCl; (S)-3'-(Trifluoromethyl)phenethylamine hydrochloride; (S)-1-(3-(Trifluoromethyl)phenyl)ethan-1-amine hydrochloride; (S)-TFMPEA HCl; (S)-1-(m-Trifluoromethylphenyl)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our production of (S)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine-Hcl adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer and research standards. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.