Description

(1R)(3-Chlorophenyl)Cyclopropylmethylamine CAS NO 1213903-33-3 is a chiral amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopropylmethylamine moiety attached to a chlorinated aromatic ring, makes it a valuable precursor for the development of novel pharmaceutical compounds and fine chemicals. This high-purity intermediate is primarily utilized by research institutions and chemical manufacturers engaged in medicinal chemistry, process development, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities.
• Asymmetric Synthesis: Serves as a building block for constructing complex molecules requiring the (1R) stereochemical configuration.
• Agrochemical Development: Potential intermediate in the synthesis of novel herbicides or pesticides with specific activity profiles.
• Ligand and Catalyst Preparation: Can be utilized to create chiral ligands for asymmetric catalysis or metal complexes.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for advanced material science applications.

Basic Information

Product Name	(1R)(3-Chlorophenyl)Cyclopropylmethylamine
CAS No.	1213903-33-3
Molecular Formula	C10H12ClN
Molecular Weight	181.66 g/mol
Synonyms	(1R)-1-(3-Chlorophenyl)-2-cyclopropylethanamine; (R)-1-(3-Chlorophenyl)-2-cyclopropylethanamine; (R)-1-(3-Chlorophenyl)-2-cyclopropylethylamine; (R)-2-Cyclopropyl-1-(3-chlorophenyl)ethanamine; (R)-3-Chlorophenylcyclopropylmethylamine; (R)-CPMA; (1R)-CPMA; (R)-1-(3-Chlorophenyl)-2-cyclopropanemethanamine
EINECS	Contact for details

Quality Control

Our (1R)(3-Chlorophenyl)Cyclopropylmethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.