Description

(1S)-1-(5-Chloro(3-Pyridyl))Ethylamine Dihydrochloride is a high-purity chiral amine derivative of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical chiral building block and intermediate, enabling the development of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, targeted pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new reaction pathways in organic chemistry.
• Fine Chemical Production: Acts as a building block for other high-value, complex specialty chemicals.

Basic Information

Product Name	(1S)-1-(5-Chloro(3-Pyridyl))Ethylamine Dihydrochloride
CAS No.	1213887-83-2
Molecular Formula	C7H9ClN2 • 2HCl
Molecular Weight	241.98 g/mol
Synonyms	(S)-1-(5-Chloropyridin-3-yl)ethan-1-amine dihydrochloride; (1S)-1-(5-Chloro-3-pyridinyl)ethylamine dihydrochloride; (S)-α-Methyl-5-chloro-3-pyridinemethanamine dihydrochloride; 5-Chloro-3-pyridineethanamine, α-methyl-, (S)-, dihydrochloride; (S)-1-(5-Chloro-pyridin-3-yl)-ethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (1S)-1-(5-Chloro(3-Pyridyl))Ethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.