Description

(R)-1-(3-Fluoro-2-Methylphenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for the synthesis of complex pharmaceutical intermediates. This compound matters because its specific stereochemistry and fluorine-substituted aromatic ring make it a critical precursor in the development of targeted active pharmaceutical ingredients (APIs). Pharmaceutical R&D and fine chemical synthesis companies need this material to create novel drug candidates, particularly in therapeutic areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to introduce the (R)-configured amine functionality.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Precursor for Fluorinated Compounds: Serves as a starting material for synthesizing more complex molecules containing the 3-fluoro-2-methylphenyl moiety.
• Ligand and Catalyst Development: Potential use in the preparation of chiral ligands for catalytic asymmetric transformations.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	(R)-1-(3-Fluoro-2-Methylphenyl)Ethanamine Hydrochloride
CAS No.	1213876-59-5
Molecular Formula	C9H13ClFN
Molecular Weight	189.66 g/mol
Synonyms	(R)-1-(3-Fluoro-2-methylphenyl)ethan-1-amine hydrochloride; (R)-α-Methyl-3-fluoro-2-methylbenzylamine hydrochloride; (R)-1-(3-Fluoro-o-tolyl)ethylamine hydrochloride; (R)-3'-Fluoro-2'-methylamphetamine hydrochloride; (R)-FMA HCl; (R)-1-(3-Fluoro-2-methylphenyl)ethylamine HCl; (R)-1-Aminoethyl-3-fluoro-2-methylbenzene hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Fluoro-2-Methylphenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.