Description

(S)-2-Methyl-1-(p-Tolyl)Propan-1-Amine Hydrochloride is a high-purity chiral amine salt of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is essential for research and production in pharmaceutical, agrochemical, and specialty chemical sectors where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Used in the synthesis of chiral active ingredients for herbicides, fungicides, and pesticides, where specific stereochemistry can influence biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in homogeneous catalysis, such as asymmetric hydrogenation.
• Fine Chemical Production: A valuable intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	(S)-2-Methyl-1-(p-Tolyl)Propan-1-Amine Hydrochloride
CAS No.	1213650-06-6
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol
Synonyms	(S)-1-(4-Methylphenyl)-2-methylpropylamine hydrochloride; (S)-α,2-Dimethyl-4-methylbenzenepropanamine hydrochloride; (S)-2-Methyl-1-(4-methylphenyl)propan-1-amine hydrochloride; (S)-1-(p-Tolyl)-2-methylpropylamine HCl; (S)-p-Methylamphetamine hydrochloride (Note: for chemical reference only); (S)-1-(4-Methylphenyl)-2-methyl-1-propylamine HCl; (S)-2-Methyl-1-(4-tolyl)propan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Methyl-1-(p-Tolyl)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity (Assay), enantiomeric excess (ee), and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.