Description

3-((1R)-1-Aminoethyl)-4-Bromophenol is a chiral, halogenated phenolic amine building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a stereogenic center and both phenolic and amino functional groups, makes it a versatile intermediate for constructing complex, biologically active molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the bromophenol moiety can contribute to biological activity.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Monomer: Potential monomer for the synthesis of specialty polymers and resins with unique thermal or optical properties.
• Chemical Biology Probe: Useful for modifying peptides or proteins to study biological interactions or create targeted conjugates.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-((1R)-1-Aminoethyl)-4-Bromophenol
CAS No.	1213631-15-2
Molecular Formula	C8H10BrNO
Molecular Weight	216.08 g/mol
Synonyms	4-Bromo-3-[(1R)-1-aminoethyl]phenol; (R)-3-(1-Aminoethyl)-4-bromophenol; 4-Bromo-3-[(R)-1-aminoethyl]phenol; 3-[(1R)-1-Aminoethyl]-4-bromophenol; 1213631-15-2; (R)-1-(4-Bromo-3-hydroxyphenyl)ethan-1-amine; 4-Bromo-3-((R)-1-aminoethyl)phenol; 3-(1-Aminoethyl)-4-bromophenol (R-enantiomer)
EINECS	Contact for details

Quality Control

Our production of 3-((1R)-1-Aminoethyl)-4-Bromophenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques, including chiral HPLC to confirm enantiomeric excess (ee) and NMR for structural verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is hygroscopic and may degrade upon exposure to moisture and air. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.