Description

(R)-2-Methyl-1-(p-Tolyl)Propan-1-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined intermediate essential for creating molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and other complex chiral molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Intermediate in the synthesis of advanced chiral pesticides and herbicides, where specific stereochemistry can influence efficacy and environmental safety.
• Ligand and Catalyst Development: Building block for creating novel chiral ligands and organocatalysts used in homogeneous catalysis.
• Academic and Industrial R&D: Serves as a reference standard and starting material in chemical research exploring new synthetic methodologies.

Basic Information

Product Name	(R)-2-Methyl-1-(p-Tolyl)Propan-1-Amine Hydrochloride
CAS No.	1213611-38-1
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol
Synonyms	(R)-1-(4-Methylphenyl)-2-methylpropylamine hydrochloride; (R)-α,2-Dimethyl-4-methylbenzenepropanamine hydrochloride; (R)-2-Methyl-1-(4-methylphenyl)propan-1-amine hydrochloride; (R)-p-Methylamphetamine hydrochloride (enantiomer); (R)-1-(p-Tolyl)-2-methylpropylamine hydrochloride; (R)-4-Methylamphetamine HCl; (R)-1-Amino-2-methyl-1-(4-methylphenyl)propane hydrochloride
EINECS	Contact for details

Quality Control

Our production of (R)-2-Methyl-1-(p-Tolyl)Propan-1-Amine Hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.