Description

4-((1R)-1-Amino-2-Methylpropyl)Benzenecarbonitrile-Hcl is a high-purity chiral amine derivative, specifically the hydrochloride salt of a benzonitrile-substituted amino acid analog. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with defined stereochemistry. It is essential for research and development in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic processes to induce enantioselectivity.
• Peptidomimetics Research: Serves as a non-natural amino acid analog in the design of peptide-like compounds for drug discovery.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study biological pathways and protein functions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	4-((1R)-1-Amino-2-Methylpropyl)Benzenecarbonitrile-Hcl
CAS No.	1213584-51-0
Molecular Formula	C11H15ClN2
Molecular Weight	210.70 g/mol
Synonyms	(R)-4-(1-Amino-2-methylpropyl)benzonitrile hydrochloride; (1R)-1-Amino-2-methylpropylbenzonitrile hydrochloride; 4-[(1R)-1-Amino-2-methylpropyl]benzonitrile hydrochloride; Benzonitrile, 4-[(1R)-1-amino-2-methylpropyl]-, hydrochloride; (R)-α-Aminoisobutyl-4-cyanobenzene hydrochloride; 4-(1-Amino-2-methylpropyl)benzonitrile HCl (enantiomerically pure); (R)-4-(1-Amino-2-methylpropyl)phenyl cyanide hydrochloride
EINECS	Contact for details

Quality Control

Our 4-((1R)-1-Amino-2-Methylpropyl)Benzenecarbonitrile-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.