Description

(R)-4-(Pyrrolidin-2-Yl)Benzoic Acid is a chiral, non-natural amino acid derivative featuring a benzoic acid moiety linked to a pyrrolidine ring. This compound is a crucial chiral building block and intermediate in modern pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Asymmetric Synthesis: Serves as a versatile chiral scaffold or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Peptidomimetics & Bioisosteres: Used in the design and construction of peptidomimetic compounds where the pyrrolidine-benzoic acid structure mimics peptide motifs.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for studying biological pathways and target engagement.
• Agrochemical Research: Acts as an intermediate in the discovery of novel, chiral agrochemicals such as herbicides and fungicides.
• Material Science: Potential monomer or functional unit for creating specialized polymers with unique chiral or optical properties.

Basic Information

Product Name	(R)-4-(Pyrrolidin-2-Yl)Benzoic Acid
CAS No.	1213517-69-1
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(R)-4-(2-Pyrrolidinyl)benzoic acid; (R)-2-(4-Carboxyphenyl)pyrrolidine; 4-[(2R)-Pyrrolidin-2-yl]benzoic Acid; (R)-4-(Pyrrolidin-2-yl)benzenecarboxylic acid; (R)-BA-Pyrrolidine; (R)-BA-Pyr; (R)-4-Pyrrolidin-2-yl-benzoic acid; (R)-2-(4-Carboxy-phenyl)-pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-4-(Pyrrolidin-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. We support development from milligram to kilogram scale with consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.