Description

(1R)-2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propylamine CAS NO 1213313-27-9 is a chiral amine building block of significant interest in advanced organic synthesis. Its value lies in the combination of a stereogenic center and a trifluoromethylphenyl group, which are crucial motifs for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand Synthesis: Serves as a starting material for creating chiral ligands used in asymmetric catalysis, such as for hydrogenation or C-C bond-forming reactions.
• Advanced Material Precursor: Can be incorporated into specialty polymers or liquid crystals to impart specific optical or electronic properties.
• Chemical Biology Probe Development: Utilized in constructing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	(1R)-2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propylamine
CAS No.	1213313-27-9
Molecular Formula	C11H14F3N
Molecular Weight	217.23 g/mol
Synonyms	(1R)-1-[4-(Trifluoromethyl)phenyl]-2-methylpropylamine; (R)-1-[4-(Trifluoromethyl)phenyl]-2-methylpropan-1-amine; (R)-2-Methyl-1-[4-(trifluoromethyl)phenyl]propan-1-amine; (R)-α,α-Dimethyl-4-(trifluoromethyl)benzylamine; (R)-1-(4-Trifluoromethylphenyl)-2-methylpropylamine; (R)-2-Methyl-1-(4-trifluoromethylphenyl)propylamine; (1R)-2-Methyl-1-(4-trifluoromethylphenyl)propylamine
EINECS	Contact for details

Quality Control

Our (1R)-2-Methyl-1-[4-(Trifluoromethyl)Phenyl]Propylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity determination by HPLC, identity confirmation by IR and NMR, and quantification of organic and inorganic impurities. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.