Description

(S)-1-(2,3-Dimethylphenyl)Propan-1-Amine Hydrochloride is a high-purity chiral amine salt, a key building block in advanced organic synthesis. Its defined stereochemistry is critical for producing enantiomerically pure compounds, ensuring predictable biological activity and efficacy. This intermediate is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides, where the specific stereoisomer can significantly impact biological activity and environmental safety.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis to induce stereoselectivity in chemical reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require a specific enantiomeric form.
• Academic & Industrial R&D: A valuable compound for medicinal chemistry research, process development, and scaling up synthetic routes in laboratory and pilot plant settings.

Basic Information

Product Name	(S)-1-(2,3-Dimethylphenyl)Propan-1-Amine Hydrochloride
CAS No.	1213152-85-2
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol (Free base: 163.26 g/mol)
Synonyms	(S)-1-(2,3-Dimethylphenyl)propan-1-amine hydrochloride; (S)-1-(2,3-Dimethylphenyl)propylamine hydrochloride; (S)-2,3-Dimethyl-α-ethylbenzylamine hydrochloride; (S)-1-Amino-1-(2,3-dimethylphenyl)propane hydrochloride; (S)-α-Ethyl-2,3-dimethylbenzylamine hydrochloride; (S)-1-(2,3-Xylyl)propylamine hydrochloride
EINECS	Contact for details

Quality Control

Our production of (S)-1-(2,3-Dimethylphenyl)Propan-1-Amine Hydrochloride adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.