Description

(3R)-3-(4-Methylphenyl)Morpholine is a chiral morpholine derivative of significant interest in advanced organic synthesis. This compound serves as a valuable pharmaceutical intermediate and chiral building block for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries, where high-purity, stereochemically defined intermediates are critical for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the development of new chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Material Science: Potential monomer or precursor for designing chiral polymers and advanced functional materials.
• Academic & R&D: Serves as a standard or starting material in methodological studies and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(3R)-3-(4-Methylphenyl)Morpholine
CAS No.	1213118-87-6
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(R)-3-(p-Tolyl)morpholine; (3R)-3-(4-Methylphenyl)-morpholine; (R)-3-(4-Methylphenyl)morpholine; 4-Methylphenyl-3R-morpholine; Morpholine, 3-(4-methylphenyl)-, (3R)-; (R)-3-(4-Methylphenyl)tetrahydro-2H-1,4-oxazine
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including chiral purity analysis by HPLC, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.