Description

(R)-1-(3-Ethoxyphenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis. This compound matters as a key intermediate in the development of enantiomerically pure active pharmaceutical ingredients (APIs), where its defined stereochemistry is critical for biological activity and regulatory approval. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of novel therapeutics, particularly in central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for stereoselective transformations.
• Reference Standard: Utilized as an analytical standard for method development and quality control in chiral separation techniques like HPLC.

Basic Information

Product Name	(R)-1-(3-Ethoxyphenyl)Ethanamine Hydrochloride
CAS No.	1213097-29-0
Molecular Formula	C10H16ClNO
Molecular Weight	201.69 g/mol
Synonyms	(R)-1-(3-Ethoxyphenyl)ethan-1-amine hydrochloride; (R)-1-(3-Ethoxyphenyl)ethylamine hydrochloride; (R)-α-Methyl-3-ethoxybenzylamine hydrochloride; (R)-3-Ethoxy-α-methylbenzylamine hydrochloride; (R)-1-(3-Ethoxyphenyl)ethanamine HCl; (R)-1-(m-Ethoxyphenyl)ethylamine hydrochloride; (R)-1-(3-Ethoxyphenyl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Ethoxyphenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, purity, and stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.