Description

3-((2R)Pyrrolidin-2-Yl)-5-Fluoro-2-Methoxypyridine is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its unique pyrrolidine-pyridine hybrid structure, which is critical for imparting specific biological activity and stereochemical control in drug molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Drug Discovery Research: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and biochemical assays.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study enzyme function and receptor interactions.
• Process Chemistry Development: Utilized in route scouting and scale-up studies for the efficient manufacturing of candidate drugs.

Basic Information

Product Name	3-((2R)Pyrrolidin-2-Yl)-5-Fluoro-2-Methoxypyridine
CAS No.	1213093-30-1
Molecular Formula	C10H13FN2O
Molecular Weight	196.22 g/mol
Synonyms	5-Fluoro-2-methoxy-3-[(2R)-2-pyrrolidinyl]pyridine; (R)-5-Fluoro-2-methoxy-3-(pyrrolidin-2-yl)pyridine; 3-[(2R)-Pyrrolidin-2-yl]-5-fluoro-2-methoxypyridine; 5-Fluoro-3-((R)-pyrrolidin-2-yl)-2-methoxypyridine; 2-Methoxy-5-fluoro-3-[(2R)-2-pyrrolidinyl]pyridine; CAS 1213093-30-1
EINECS	Contact for details

Quality Control

Our 3-((2R)Pyrrolidin-2-Yl)-5-Fluoro-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.