Description

3-((1R)Aminocyclopropylmethyl)Benzoic Acid is a chiral, non-natural amino acid derivative featuring a cyclopropane ring, a key structural motif in medicinal chemistry. This compound serves as a versatile and high-value pharmaceutical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of targeted therapeutics, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• Protease Inhibitor Development: Used in constructing molecular scaffolds for inhibitors targeting specific proteases.
• Chiral Ligand Synthesis: Serves as a precursor for creating chiral ligands and catalysts used in asymmetric synthesis.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Chemical Biology Research: Employed as a tool compound for probing enzyme function and studying biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	3-((1R)Aminocyclopropylmethyl)Benzoic Acid
CAS No.	1213024-48-6
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(1R)-1-[3-(Aminomethyl)phenyl]cyclopropanamine; Benzoic acid, 3-[(1R)-1-aminocyclopropyl]methyl]-; (R)-3-((1-Aminocyclopropyl)methyl)benzoic acid; (R)-3-(1-Aminocyclopropylmethyl)benzoic Acid; 3-[(1R)-1-Aminocyclopropyl]methyl]benzoic acid; (R)-3-(Aminocyclopropylmethyl)benzoic Acid; 1213024-48-6; (R)-3-((1-Aminocyclopropyl)methyl)benzoate
EINECS	Contact for details

Quality Control

Our 3-((1R)Aminocyclopropylmethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.