Description

(S)-1-(m-Tolyl)Propan-1-Amine Hydrochloride CAS NO 1212973-31-3 is a high-purity chiral amine derivative, specifically the hydrochloride salt of the (S)-enantiomer. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the production of enantiomerically pure pharmaceuticals and agrochemicals. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries who require high-quality, stereochemically defined intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective reactions to create enantiomerically enriched compounds.
• Agrochemical Research: Intermediate in the development of novel, chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Building block for creating chiral ligands used in metal-catalyzed asymmetric transformations.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in regulatory submissions.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and process chemistry for exploring new synthetic routes.

Basic Information

Product Name	(S)-1-(m-Tolyl)Propan-1-Amine Hydrochloride
CAS No.	1212973-31-3
Molecular Formula	C10H15N·HCl
Molecular Weight	185.69 g/mol
Synonyms	(S)-1-(3-Methylphenyl)propan-1-amine hydrochloride; (S)-1-(m-Tolyl)ethylamine hydrochloride (common misnomer, often used); (S)-α-Methyl-m-toluidine hydrochloride; (S)-1-(3-Methylphenyl)propylamine hydrochloride; (S)-m-Tolylpropylamine hydrochloride; (S)-3-Methylbenzenepropanamine hydrochloride; (S)-1-Amino-1-(3-methylphenyl)propane hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(m-Tolyl)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) for assay, enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.