Description

(1R)Cyclopropyl(3-Methoxyphenyl)Methylamine-Hcl CAS NO 1212958-89-8 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its defined stereochemistry and functional groups.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the development of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the creation of advanced, chiral pesticides and herbicides where specific stereochemistry impacts efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Catalyst & Ligand Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic & Institutional Research: A valuable compound for methodological development in organic synthesis and stereochemistry at universities and research institutes.

Basic Information

Product Name	(1R)Cyclopropyl(3-Methoxyphenyl)Methylamine Hydrochloride
CAS No.	1212958-89-8
Molecular Formula	C12H17NO • HCl
Molecular Weight	227.73 g/mol (free base: 191.27 g/mol)
Synonyms	(1R)-1-Cyclopropyl-1-(3-methoxyphenyl)methanamine hydrochloride; (R)-1-Cyclopropyl-1-(3-methoxyphenyl)methylamine HCl; (R)-α-Cyclopropyl-3-methoxybenzylamine hydrochloride; (R)-CPMA-HCl; (1R)-[Cyclopropyl(3-methoxyphenyl)methyl]amine hydrochloride; (R)-1-(3-Methoxyphenyl)-1-cyclopropylmethanamine hydrochloride; (R)-O-Methyl-α-cyclopropylbenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1R)Cyclopropyl(3-Methoxyphenyl)Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards suitable for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.