Description

(R)-1-(m-Tolyl)Propan-1-Amine Hydrochloride CAS NO 1212925-87-5 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a defined stereocenter essential for creating enantiomerically pure compounds with specific biological activity. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry enhances efficacy and reduces environmental impact.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control reaction stereoselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry and process development for scale-up.

Basic Information

Product Name	(R)-1-(m-Tolyl)Propan-1-Amine Hydrochloride
CAS No.	1212925-87-5
Molecular Formula	C10H16ClN
Molecular Weight	185.69 g/mol
Synonyms	(R)-1-(3-Methylphenyl)propan-1-amine hydrochloride; (R)-1-(m-Tolyl)-1-propylamine hydrochloride; (R)-α-Methyl-3-methylbenzeneethanamine hydrochloride; (R)-3-Methyl-α-ethylbenzenemethanamine hydrochloride; (R)-1-(3-Methylphenyl)propylamine hydrochloride; (R)-m-Tolylpropylamine hydrochloride; (R)-1-Amino-1-(3-methylphenyl)propane hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(m-Tolyl)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical development. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), enantiomeric excess (ee), and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.