Description

(1S)-1-[4-(tert-Butyl)Phenyl]Propylamine is a chiral amine building block of significant importance in advanced organic synthesis. Its value lies in its well-defined stereochemistry and the tert-butylphenyl moiety, which are crucial for modulating the physical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a precursor or resolving agent in the preparation of chiral catalysts and auxiliaries for enantioselective transformations.
• Agrochemical Research: Serves as a building block for the synthesis of advanced, stereochemically-defined pesticides and herbicides.
• Material Science: Potential monomer or functionalization agent for specialty polymers and advanced organic materials requiring specific steric and electronic properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.

Basic Information

Product Name	(1S)-1-[4-(tert-Butyl)Phenyl]Propylamine
CAS No.	1212887-14-3
Molecular Formula	C₁₃H₂₁N
Molecular Weight	191.31 g/mol
Synonyms	(S)-1-(4-tert-Butylphenyl)propylamine; (S)-1-[4-(1,1-Dimethylethyl)phenyl]-1-propanamine; (S)-1-(p-tert-Butylphenyl)propylamine; (1S)-1-[4-(1,1-Dimethylethyl)phenyl]propan-1-amine; (S)-(-)-1-(4-tert-Butylphenyl)propylamine; (S)-1-(4-tert-Butylphenyl)propan-1-amine; (S)-α-Methyl-4-tert-butylbenzylamine
EINECS	Contact for details

Quality Control

Our (1S)-1-[4-(tert-Butyl)Phenyl]Propylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and optical rotation values are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Optical Rotation [α]	Specified value ± 0.5°
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.