Description

(2R)-2-Amino-2-(4-Fluoro-2-Methylphenyl)Acetic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a fluorinated aromatic side chain. This compound is a critical chiral building block in modern pharmaceutical synthesis, enabling the development of targeted therapeutics with enhanced efficacy and metabolic stability. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in the areas of enzyme inhibitors and receptor modulators.

Application

• Key chiral intermediate in the synthesis of novel pharmaceutical candidates.
• Building block for peptide mimetics and constrained peptide analogs in drug discovery.
• Precursor for the development of enzyme inhibitors targeting specific biological pathways.
• Starting material for research into fluorinated bioactive compounds.
• Intermediate in the preparation of diagnostic agents and imaging probes.
• Used in asymmetric synthesis to introduce a chiral, fluorinated phenylglycine moiety.

Basic Information

Product Name	(2R)-2-Amino-2-(4-Fluoro-2-Methylphenyl)Acetic Acid
CAS No.	1212807-45-8
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	(R)-2-Amino-2-(4-Fluoro-2-methylphenyl)acetic acid; D-4-Fluoro-2-methylphenylglycine; (2R)-Amino(4-fluoro-2-methylphenyl)acetic acid; (R)-4-Fluoro-2-methyl-α-aminophenylacetic acid; (R)-α-Amino-4-fluoro-2-methylbenzeneacetic acid; (R)-2-(4-Fluoro-2-methylphenyl)glycine; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-2-(4-Fluoro-2-Methylphenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.