Description

(2R)-Morpholine-2-Carboxylic Acid CAS NO 1212396-52-5 is a chiral, non-proteinogenic amino acid derivative featuring a morpholine ring. This compound matters as a versatile and high-value building block for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for creating novel therapeutics and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of APIs, especially for central nervous system (CNS) drugs, antivirals, and enzyme inhibitors.
• Peptidomimetics & Drug Discovery: Used to introduce constrained morpholine scaffolds into peptide analogs to enhance metabolic stability, bioavailability, and receptor selectivity.
• Ligand & Catalyst Synthesis: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme mechanisms and protein-protein interactions.
• Agrochemical Research: Employed in the development of novel, chiral active ingredients for crop protection.
• Material Science: Potential monomer for creating specialized polymers with unique properties.

Basic Information

Product Name	(2R)-Morpholine-2-Carboxylic Acid
CAS No.	1212396-52-5
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	(R)-Morpholine-2-carboxylic acid; (2R)-Tetrahydro-1,4-oxazine-2-carboxylic acid; D-Morpholine-2-carboxylic acid; (R)-2-Morpholinecarboxylic acid; (R)-MOCCA; L-000637759; 2-Morpholinecarboxylic acid, (2R)-; Tetrahydro-2H-1,4-oxazine-2-carboxylic acid, (2R)-
EINECS	Contact for details

Quality Control

Our (2R)-Morpholine-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and enantiomeric excess (e.e.), meeting the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.