Description

tert-Butyl cis-4-(3-Hydroxypropyl)Cyclohexylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutics targeting metabolic and inflammatory pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in process development and scale-up for new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, particularly those with cyclohexylamine-based structures.
• Protease Inhibitor Research: Used in the research and development of protease inhibitors, where the carbamate and hydroxyl functionalities are essential for activity.
• Peptidomimetic Synthesis: Serves as a crucial component for constructing peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme mechanisms and protein-ligand interactions in metabolic diseases.
• Process Chemistry Development: Utilized by process chemists for route scouting, optimization, and the development of robust, scalable manufacturing processes for APIs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	tert-Butyl cis-4-(3-Hydroxypropyl)Cyclohexylcarbamate
CAS No.	1212377-95-1
Molecular Formula	C14H27NO3
Molecular Weight	257.37 g/mol
Synonyms	cis-4-(3-Hydroxypropyl)cyclohexylcarbamic acid tert-butyl ester; tert-Butyl N-[cis-4-(3-hydroxypropyl)cyclohexyl]carbamate; 4-(3-Hydroxypropyl)cyclohexylcarbamic Acid 1,1-Dimethylethyl Ester (cis-); BOC-cis-4-(3-Hydroxypropyl)cyclohexylamine; (cis-4-(3-Hydroxypropyl)cyclohexyl)carbamic acid tert-butyl ester; N-Boc-cis-4-(3-hydroxypropyl)cyclohexanamine
EINECS	Contact for details

Quality Control

Our tert-Butyl cis-4-(3-Hydroxypropyl)Cyclohexylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (Chiral HPLC)	≥99.0% cis-isomer
Related Substances (HPLC)	Total impurities ≤1.5%
Any single impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.